First example of ring carbomer of 1,4-cyclohexadiene

Cécile Barthes, Arnaud Rives, Valérie Maraval, Evelyne Chelain, Thierry Brigaud, Remi Chauvin


While a series of carbo-mers of 1,3-cyclohexadienes was reported through the use of a specifically developed synthetic strategy, no example of their 1,4-regioisomers was known. Inspired by the methodology elaborated for the preparation of the 1,3-isomers, the synthesis of the first example of carbo-mer of 1,4-cyclohexadiene is presented. Comparison of physico-chemical properties of this first representative with those of the recently described 1,4-regioisomer, especially UV-vis absorption properties, is also addressed.


butatrienes; carbo-cyclohexadienes; carbo-mers; nucleophilic trifluoromethylation

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