Visual-test and Sorption-spectrophotometric Determination of Melamine in Biological Objects

Authors

  • Olga A. Zaporozhets Department of Chemistry, Taras Shevchenko National University of Kyiv, 12 Lva Tolstogo street, Kyiv, 01033, Ukraine
  • Natalia I. Smyk Department of Chemistry, Taras Shevchenko National University of Kyiv, 12 Lva Tolstogo street, Kyiv, 01033, Ukraine
  • Daria O. Rudakova Department of Chemistry, Taras Shevchenko National University of Kyiv, 12 Lva Tolstogo street, Kyiv, 01033, Ukraine

DOI:

https://doi.org/10.17721/fujcV3I2P125-130

Keywords:

melamine, sorption-spectroscopic method, visual test-method, food, beverages

Abstract

Melamine may have toxic effects on humans and animals. It is well known that melamine accumulates in the body and causes reproductive damages, forms bladder or kidney stones, which can lead to bladder cancer. Trace amounts of melamine at ppm levels may occur in certain food commodities due to its migration from melamine-containing disposable tableware plastics. It was intentionally adulterated to milk products to show a false increase in protein concentration. Considering these facts there is a need for establishing sensitive and reliable methods of melamine determination. As uncostly, rapid and selective melamine detection methods are highly required, the hyphenated sorption-spectrophotometric and visual test methods seem to be perspective candidates.

In the present work the optimal conditions of sorption concentration of melamine from aqueous solutions ontо the silica gel surface were studied. The calibration graph for the sorption-spectrophotometric method is linear in 0.02 – 9.8 μmol.L-1 mg L-1 melamine concentration range. Proposed method allows naked-eye monitoring of biological samples.

 

References

Ishiwata H, Yamazaki T, Yoshihira K, J . of the Association of Offitial Analytical Chemists. J Assoc Off Anal Chem 1987;70(3):457-460. Available from: http://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+108-78-1 PubMed PMID: 3610957.

Tyan Y, Yang M, Jong S, Wang C, Shiea J. Melamine contamination. Anal Bioanal Chem 2009;395(3):729-735. https://doi.org/10.1007/s00216-009-3009-0

Zhu H, Zhang S, Li M, Shao Y, Zhu Z. Electrochemical sensor for melamine based on its copper complex. Chemical Communications 2010;46(13):2259. https://doi.org/10.1039/b924355k

Wang C, Qin X, Huang B, He F, Zeng C. Hemolysis of human erythrocytes induced by melamine–cyanurate complex. Biochemical and Biophysical Research Communications 2010;402(4):773-777. https://doi.org/10.1016/j.bbrc.2010.10.108

Ma C, Kang H, Liu Q, Zhu R, Cao Z. Insight into potential toxicity mechanisms of melamine: An in silico study. Toxicology 2011;283(2-3):96-100. https://doi.org/10.1016/j.tox.2011.02.009

Chan E, Griffiths S, Chan C. Public-health risks of melamine in milk products. The Lancet 2008;372(9648):1444-1445. https://doi.org/10.1016/s0140-6736(08)61604-9

Lam C, Lan L, Che X, Tam S, Wong S, Chen Y, Jin J, Tao S, Tang X, Yuen K, Tam P. Diagnosis and spectrum of melamine-related renal disease: Plausible mechanism of stone formation in humans. Clinica Chimica Acta 2009;402(1-2):150-155. https://doi.org/10.1016/j.cca.2008.12.035

Hau A, Kwan T, Li P. Melamine Toxicity and the Kidney. Journal of the American Society of Nephrology 2009;20(2):245-250. https://doi.org/10.1681/asn.2008101065

Muñiz-Valencia R, Ceballos-Magaña S, Rosales-Martinez D, Gonzalo-Lumbreras R, Santos-Montes A, Cubedo-Fernandez-Trapiella A, Izquierdo-Hornillos R. Method development and validation for melamine and its derivatives in rice concentrates by liquid chromatography. Application to animal feed samples. Anal Bioanal Chem 2008;392(3):523-531. https://doi.org/10.1007/s00216-008-2294-3

Ono S, Funato T, Inoue Y, Munechika T, Yoshimura T, Morita H, Rengakuji S, Shimasaki C. Determination of melamine derivatives, melame, meleme, ammeline and ammelide by high-performance cation-exchange chromatography. Journal of Chromatography A 1998;815(2):197-204. https://doi.org/10.1016/s0021-9673(98)00441-5

Sun H, Wang L, Ai L, Liang S, Wu H. A sensitive and validated method for determination of melamine residue in liquid milk by reversed phase high-performance liquid chromatography with solid-phase extraction. Food Control 2010;21(5):686-691. https://doi.org/10.1016/j.foodcont.2009.10.008

Wu Y, Huang C, Lin C, Ho W, Lin L, Chiu T, Tarng D, Lin C, Tsai T. Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography–tandem mass spectrometry. Journal of Chromatography A 2009;1216(44):7595-7601. https://doi.org/10.1016/j.chroma.2009.05.027

Xu X, Ren Y, Zhu Y, Cai Z, Han J, Huang B, Zhu Y. Direct determination of melamine in dairy products by gas chromatography/mass spectrometry with coupled column separation. Analytica Chimica Acta 2009;650(1):39-43. https://doi.org/10.1016/j.aca.2009.04.026

Garber E. J Food Protect. 2008;71(590):590-594.

Wei F, Lam R, Cheng S, Lu S, Ho D, Li N. Rapid detection of melamine in whole milk mediated by unmodified gold nanoparticles. Appl. Phys. Lett. 2010;96(13):133702. https://doi.org/10.1063/1.3373325

Rima J, Abourida M, Xu T, Cho I, Kyriacos S. New spectrophotometric method for the quantitative determination of melamine using Mannich reaction. Journal of Food Composition and Analysis 2009;22(7-8):689-693. https://doi.org/10.1016/j.jfca.2009.02.010

Zhou Y, Yang J, Liu M, Wang S, Lu Q. A novel fluorometric determination of melamine using cucurbit[7]uril. Journal of Luminescence 2010;130(5):817-820. https://doi.org/10.1016/j.jlumin.2009.12.001

Attia M, Bakir E, Abdel-aziz A, Abdel-mottaleb M. Determination of melamine in different milk batches using a novel chemosensor based on the luminescence quenching of Ru(II) carbonyl complex. Talanta 2011;84(1):27-33. https://doi.org/10.1016/j.talanta.2010.11.071

Liu Y, Deng J, An L, Liang J, Chen F, Wang H. Spectrophotometric determination of melamine in milk by rank annihilation factor analysis based on pH gradual change-UV spectral data. Food Chemistry 2011;126(2):745-750. https://doi.org/10.1016/j.foodchem.2010.11.057

Zaporozhets O, Petruniock N, Sukhan V. Determination of Ag(I), Hg(II) and Pb(II) by using silica gel loaded with dithizone and zinc dithizonate. Talanta 1999;50(4):865-873. https://doi.org/10.1016/s0039-9140(99)00172-1

Liang R, Zhang R, Qin W. Potentiometric sensor based on molecularly imprinted polymer for determination of melamine in milk. Sensors and Actuators B: Chemical 2009;141(2):544-550. https://doi.org/10.1016/j.snb.2009.05.024

ZAPOROZHETS O, TSYUKALO L. Xylenol orange adsorbed on silica surface as a solid phase reagent for lead determination using diffuse reflectance spectroscopy. Talanta 2002;58(5):861-868. https://doi.org/10.1016/s0039-9140(02)00402-2

Downloads

Additional Files

Published

2015-12-30

Issue

Vol. 3 No. 2 (2015): Proceedings of the VIII International scientific conference “Kiev-Toulouse”

Section

Articles

License

Copyright (c) 2015 French-Ukrainian Journal of Chemistry

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

The French‑Ukrainian Journal of Chemistry holds copyright and publishes all articles under a Creative Commons Attribution 4.0 International licence (CC BY 4.0).
This license permits unrestricted use, sharing, adaptation, distribution, and reproduction in any medium or format, provided that the original author(s) and source are credited, a link to the license is included, and any changes made are indicated.
Authors grant the French‑Ukrainian Journal of Chemistry the exclusive right of first publication and may enter into separate, non‑exclusive distribution agreements for the published version (e.g., institutional repository, book chapter). Authors are also encouraged to post pre‑prints and post‑prints online to increase visibility and citation.